Articles tagged with: Sean R_ Hosein

Syphilis cases on the rise among HIV-positive people in Calgary

published: March, 27, 2018 Written by // CATIE - HIV and Hep C Info Resource Categories // Social Media, Gay Men, CATIE, Research, Health, CATIE - HIV and Hep C Info Resource, Sexual Health, Media

"The Calgary study underscores the need for regular, perhaps even frequent, screening for syphilis among sexually active HIV-positive people." From CATIE, Sean R. Hosein reports.

Syphilis cases on the rise among HIV-positive people in Calgary

- Calgary doctors noticed a three-fold increase in syphilis among patients with HIV - Syphilis was more common among people with HIV not taking treatment - More than half of cases had no symptoms, highlighting the need for screening Syphilis cases decreased in the 1990s but began to increase in Canada and other high-income countries around the year 2000. This increase has disproportionally affected gay, bisexual and other men who have sex with men (MSM), including those who are HIV positive

Patterns of substance use associated with fentanyl exposure in Vancouver

published: March, 12, 2018 Written by // CATIE - HIV and Hep C Info Resource Categories // Social Media, Current Affairs, Research, Health, CATIE - HIV and Hep C Info Resource, Media

From CATIE, Sean R. Hosein reports on a Vancouver study aiming to find out about the degree of exposure to fentanyl among people who use street drugs.

Patterns of substance use associated with fentanyl exposure in Vancouver

- British Columbia researchers analyzed urine samples of 669 people who used street drugs - 15% of all participants had been exposed to the extremely powerful opioid fentanyl - Exposure to fentanyl was higher among those who inject drugs In the past several years, deaths from opioid overdose have increased in Canada and the U.S. In Canada the increase in deaths was initially reported in British Columbia and then spread to neighbouring Alberta and other parts of Canada. British

On-demand PEP to prevent HIV infection

published: February, 23, 2018 Written by // CATIE - HIV and Hep C Info Resource Categories // African, Caribbean and Black, Social Media, As Prevention , Gay Men, Treatment Guidelines -including when to start, Women, Health, CATIE - HIV and Hep C Info Resource, Treatment, Media

“HIV PEP-in-pocket (PIP)" designed to help those “who do not meet criteria for daily or on-demand PrEP" From CATIE, Sean R.Hosein reports.

On-demand PEP to prevent HIV infection

- Post-exposure prophylaxis (PEP) can prevent HIV infection up to 72 hours after exposure - To expedite initiation of PEP, two Toronto clinics prescribed the medication in advance - 13% of “PEP-in-pocket” prescriptions were filled, resulting in zero infections There are several options to reduce a person’s risk of becoming infected with HIV during sex. One option increasingly used in Canada and other high-income countries involves the use of a pill containing two anti-HIV medicines—

Will de-simplification of HIV treatment become common in high-income countries?

published: February, 14, 2018 Written by // CATIE - HIV and Hep C Info Resource Categories // Social Media, As Prevention , Treatment Guidelines -including when to start, Research, CATIE - HIV and Hep C Info Resource, Treatment, Media

From CATIE, Sean R. Hosein reports on a study exploring de-simplification as a cost-cutting measure.

Will de-simplification of HIV treatment become common in high-income countries?

- As more people start HIV treatment, researchers are exploring ways to cut costs - Single tablets can be replaced by a few pills comprising cheaper generic drugs - Alberta clinic projects $4.3 million saved by “de-simplifying” one treatment regimen Initiating and staying on HIV treatment (ART) results in most people having very low levels of HIV in their blood. Such low levels are commonly called undetectable and result in improved measures of health and projections of near-normal life

French study confirms the safety and effectiveness of varenicline for HIV-positive smokers

published: January, 25, 2018 Written by // CATIE - HIV and Hep C Info Resource Categories // Social Media, Research, Health, International , CATIE - HIV and Hep C Info Resource, Smoking Cessation , Media

Varenicline (combined with counselling) can clearly help some HIV-positive people to quit smoking. From CATIE, Sean R. Hosein reports.

French study confirms the safety and effectiveness of varenicline for HIV-positive smokers

- People living with HIV are known to be at increased risk for smoking-related illnesses. - Researchers find varenicline safe and effective at helping people with HIV quit smoking. - Cessation counsellors who are infectious disease specialists have higher quit rates. The widespread use of potent HIV treatment (ART) has led to improved measures of health and near-normal life expectancy for many people with HIV in Canada and other high-income countries. However, studies have found that ART us

PrEP’s social impact on the lives of some gay men in Toronto

published: January, 23, 2018 Written by // Guest Authors - Revolving Door Categories // Dating, African, Caribbean and Black, As Prevention , Gay Men, Youth, Treatment Guidelines -including when to start, Research, Health, CATIE - HIV and Hep C Info Resource, Sexual Health, Lifestyle, Treatment, Living with HIV

Researchers in Toronto conducted a PrEP demonstration project to assess its acceptability, use and effectiveness. From CATIE, Sean R. Hosein reports.

PrEP’s social impact on the lives of some gay men in Toronto

- Researchers interviewed early adopters of PrEP in Toronto about their experience. - Participants reported that their use of PrEP left them feeling “proud” and “liberated.” - Stigma and judgment related to PrEP also led some participants to conceal their use of it. PrEP (pre-exposure prophylaxis) involves taking two anti-HIV medicines in one pill, usually daily, to reduce the chance of getting HIV. PrEP is meant to be used in combination with other HIV prevention approaches, such a

Inflammation-related illness among HIV-positive people

published: December, 28, 2017 Written by // CATIE - HIV and Hep C Info Resource Categories // Social Media, General Health, Research, Health, International , CATIE - HIV and Hep C Info Resource, Living with HIV, Media

Researchers assess two studies to understand the impact of chronic inflammation on major clinical events—heart attack, stroke, cancer, other serious complications and the risk of death. From CATIE, Sean R. Hosein reports.

Inflammation-related illness among HIV-positive people

Chronic HIV infection is associated with increased levels of inflammation. Researchers suspect that over the long-term this inflammation may be associated with an increased risk of health problems. To explore this idea, rather than launch a new and expensive clinical trial, researchers in Europe and the U.S. re-analysed data from two large, well-designed studies of the cytokine IL-2 (interleukin-2) in people with HIV. Specifically, researchers sought to assess the impact of chronic inflammati

Canadian study links food insecurity to detectable viral loads and decreased CD4+ cells

published: December, 12, 2017 Written by // CATIE - HIV and Hep C Info Resource Categories // Social Media, As Prevention , Hep B and C, Food, Nutrition and Recipes, Treatment Guidelines -including when to start, Research, Health, CATIE - HIV and Hep C Info Resource, Treatment, Living with HIV, Media

Researchers propose “broad multisector interventions that address income, housing affordability, substance use and mental health issues” to address the high degree of food insecurity in their study. From CATIE, Sean R. Hosein reports.

Canadian study links food insecurity to detectable viral loads and decreased CD4+ cells

- Canadian study of people with HIV and hepatitis C co-infection finds that limited access to food is associated with higher levels of HIV in the blood and 10% fewer CD4+ immune cells. - Ontario research reports 70% of HIV-positive participants had experienced food insecurity over the past year, six times greater than HIV-negative people. - Researchers say addressing underlying food insecurity could improve treatment adherence and health outcomes of people living with HIV. Researchers who e

What’s next for long-acting HIV drugs?

published: November, 22, 2017 Written by // CATIE - HIV and Hep C Info Resource Categories // As Prevention , Current Affairs, CATIE, Treatment Guidelines -including when to start, Health, Research, CATIE - HIV and Hep C Info Resource, Treatment

Two phase III trials are underway with long-acting (LA) formulations of HIV drugs. From CATIE, Sean R. Hosein reports.

What’s next for long-acting HIV drugs?

Two phase III trials are underway with long-acting (LA) formulations of HIV drugs. These trials will explore the safety and effectiveness of LA formulations in people new to HIV treatment (Flair) and in people who are treatment experienced (Atlas). The interim results from these two pivotal studies should be available in the latter half of 2018. If the results from Flair and Atlas are favourable, the manufacturer of the LA drugs, Viiv Healthcare, will submit a dossier of the data to regulator

Canadian researchers call for improved integration of family planning care for HIV-positive women

published: November, 15, 2017 Written by // CATIE - HIV and Hep C Info Resource Categories // CATIE - HIV and Hep C Info Resource

A team of Canadian researchers has analysed a comprehensive survey of HIV-positive women living in British Columbia, Ontario and Quebec. From CATIE, Sean R. Hosein reports.

Canadian researchers call for improved integration of family planning care for HIV-positive women

- Canadian study finds 60% of pregnancies among HIV-positive women were unintended. - Among HIV-positive women, unintentional pregnancies were more common if they were younger, single or born in Canada. - Researchers highlight the need to integrate family planning within comprehensive HIV care. A team of Canadian researchers has analysed a comprehensive survey of HIV-positive women living in British Columbia, Ontario and Quebec. The survey focused on pregnancy-related issues. The researcher

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