GMSH

Research

Common birth control shot linked to risk of HIV infection

published: January, 17, 2018 Written by // Guest Authors - Revolving Door Categories // Social Media, African, Caribbean and Black, As Prevention , Treatment Guidelines -including when to start, Women, Research, Health, International , Revolving Door, Treatment, Guest Authors, Media

Research indicates alternative contraception methods may help protect women.

Common birth control shot linked to risk of HIV infection

Washington, DC - Transitioning away from a popular contraceptive shot known as DMPA could help protect women in Sub-Saharan Africa and other high-risk regions from becoming infected with HIV, according to a research review published in the Endocrine Society’s journal Endocrine Reviews. The predominant contraceptive in Sub-Saharan Africa is depot-medroxyprogesterone acetate (DMPA)—a birth control shot administered every three months. Human studies suggest DMPA use may raise the risk of H

Attitudes towards men who ‘bareback’ are a barrier to wider use of PrEP

published: January, 16, 2018 Written by // Guest Authors - Revolving Door Categories // Social Media, Gay Men, As Prevention , Treatment Guidelines -including when to start, General Health, Mental Health, Health, Research, Sexual Health, Revolving Door, Treatment, Lifestyle, Guest Authors, Media

From NAM AIDSmap, Roger Pebody reports on two Toronto studies that shed light on how PrEP stigma is affecting PrEP uptake.

Attitudes towards men who ‘bareback’ are a barrier to wider use of PrEP

Two new qualitative studies from Toronto shed light on how stigma affects the uptake of pre-exposure prophylaxis (PrEP) and the experience of taking it. In the first, young gay men acknowledged that they did not always use condoms but did not see themselves as the kind of ‘barebacker’ for whom they thought PrEP was intended. “PrEP embodies the notion of bareback sex, which traditionally has been associated with negative elements, and it is quite clear that the young gay men in this re

High prevalence of emphysema in middle-aged HIV-positive smokers

published: January, 09, 2018 Written by // Guest Authors - Revolving Door Categories // Social Media, Research, Health, International , Smoking Cessation , Revolving Door, Media, Guest Authors

From AIDSmap, Michael Carter reports on a French study that associates HIV with an increased prevalence of airway obstruction.

High prevalence of emphysema in middle-aged HIV-positive smokers

HIV infection is associated with airway obstruction, French investigators report in AIDS. Middle-aged HIV-positive smokers were matched with HIV-negative smokers of the same sex and age. After controlling for potential confounders, the investigators found a significant association between HIV and airway obstruction, an association that persisted after controlling for history of previous serious lung disease. Smoking intensity was also a significant risk factor. Lung function was measured usi

Children exposed to drugs, violence experience higher incidence of HIV as adults

published: January, 08, 2018 Written by // Guest Authors - Revolving Door Categories // Social Media, Gay Men, Youth, Research, Health, International , Revolving Door, Guest Authors, Media

“Unfortunately, data on sexual abuse and bisexual/same-sex behaviors were not collected, and these may be important factors to examine in future research.” From MDmag, this report by George Citroner.

Children exposed to drugs, violence experience higher incidence of HIV as adults

To read the complete article by George Citroner visit MD, here. Evidence suggests that exposure to certain types of mental and physical stress in adolescence may make it more likely that as adults they will practice behaviors that increase the risk of HIV infection. A longitudinal study conducted by the University of Michigan over 18 years, from Sept. 1994–May 2013, studied the effects exposure to illicit drug use, and violence had on adolescents in later adulthood. The findings sugge

Diabetes in people with HIV over 50 overwhelmingly linked to old antiretrovirals, not age or body weight

published: January, 04, 2018 Written by // Guest Authors - Revolving Door Categories // Social Media, Aging, Health, Research, International , Revolving Door, Guest Authors, Media

The onset of diabetes was much less likely in people aged 50 and over who started treatment from 2010 onwards, or who started treatment at a higher CD4 cell count, according to this B.C.study. From AIDSmap, Keith Alcorn explains.

Diabetes in people with HIV over 50 overwhelmingly linked to old antiretrovirals, not age or body weight

People with HIV over the age of 50 are more likely to have developed type 2 diabetes if they started antiretroviral treatment before 1999 or had a longer exposure to older antiretroviral drugs such as stavudine (d4T) or first-generation protease inhibitors such as nelfinavir or indinavir, according to a study of people receiving HIV care in British Columbia, Canada. The onset of diabetes was much less likely in people aged 50 and over who started treatment from 2010 onwards, or who started tr

Selective suppression of inflammation could deplete HIV and control HIV activation

published: January, 03, 2018 Written by // Guest Authors - Revolving Door Categories // Social Media, Current Affairs, Health, Research, International , Revolving Door, Guest Authors, Media

Study authors: "We are rigorously evaluating the effect of Jak inhibitors on key events that prevent eradication of HIV in culture, animal models, and humans."

Selective suppression of inflammation could deplete HIV and control HIV activation

A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could "purge" the reservoir of infected immune cells in people infected by HIV, according to new research. When culturing cells from HIV-infected individuals, researchers found the medications tofacitinib and ruxolitinib block viral production from infected cells, prevent transmission to bystander cells, and decay the viral reservoir. The results were published in PLOS Pathogens. "One of the major impediments t

Inflammation-related illness among HIV-positive people

published: December, 28, 2017 Written by // CATIE - HIV and Hep C Info Resource Categories // Social Media, General Health, Research, Health, CATIE - HIV and Hep C Info Resource, International , Living with HIV, Media

Researchers assess two studies to understand the impact of chronic inflammation on major clinical events—heart attack, stroke, cancer, other serious complications and the risk of death. From CATIE, Sean R. Hosein reports.

Inflammation-related illness among HIV-positive people

Chronic HIV infection is associated with increased levels of inflammation. Researchers suspect that over the long-term this inflammation may be associated with an increased risk of health problems. To explore this idea, rather than launch a new and expensive clinical trial, researchers in Europe and the U.S. re-analysed data from two large, well-designed studies of the cytokine IL-2 (interleukin-2) in people with HIV. Specifically, researchers sought to assess the impact of chronic inflammati

Canadian study links food insecurity to detectable viral loads and decreased CD4+ cells

published: December, 12, 2017 Written by // CATIE - HIV and Hep C Info Resource Categories // Social Media, Hep B and C, As Prevention , Food, Nutrition and Recipes, Treatment Guidelines -including when to start, Research, Health, CATIE - HIV and Hep C Info Resource, Treatment, Living with HIV, Media

Researchers propose “broad multisector interventions that address income, housing affordability, substance use and mental health issues” to address the high degree of food insecurity in their study. From CATIE, Sean R. Hosein reports.

Canadian study links food insecurity to detectable viral loads and decreased CD4+ cells

- Canadian study of people with HIV and hepatitis C co-infection finds that limited access to food is associated with higher levels of HIV in the blood and 10% fewer CD4+ immune cells. - Ontario research reports 70% of HIV-positive participants had experienced food insecurity over the past year, six times greater than HIV-negative people. - Researchers say addressing underlying food insecurity could improve treatment adherence and health outcomes of people living with HIV. Researchers who e

HIV-positive transgender men in US have significant unmet medical and social needs

published: December, 11, 2017 Written by // Guest Authors - Revolving Door Categories // Social Media, As Prevention , Gay Men, Treatment Guidelines -including when to start, Health, Research, International , Revolving Door, Treatment, Living with HIV, Guest Authors, Media

“Although these transgender men had access to HIV medical care, many experienced poor health outcomes and unmet needs,” write the authors. From AIDSmap, Michael Carter reports.

HIV-positive transgender men in US have significant unmet medical and social needs

HIV-positive transgender men in the United States have significant unmet social and healthcare needs, according to a study published in Research and Practice. Approximately half were living in poverty and only 60% had sustained viral suppression. “Many transgender men receiving HIV medical care in the United States face socioeconomic challenges and suboptimal health outcomes,” write the authors. “Although these transgender men had access to HIV medical care, many experienced poor hea

Many Americans still get their HIV diagnosis years after infection

published: December, 07, 2017 Written by // Guest Authors - Revolving Door Categories // Social Media, As Prevention , Gay Men, Treatment Guidelines -including when to start, Health, Research, International , Treatment, Revolving Door, Guest Authors, Media

Heterosexual men had undiagnosed HIV longer than women who inject drugs or gay and bisexual men (a median of about five years, two years and three years, respectively).From AIDSmap, Liz Highleyman reports.

Many Americans still get their HIV diagnosis years after infection

Many people with HIV in the United States are still being diagnosed with HIV late, and therefore not getting the full therapeutic and prevention benefits of starting antiretroviral therapy (ART) early, according to the latest Vital Signs report from the US Centers for Disease Control and Prevention (CDC), released in advance of World AIDS Day. People at risk for HIV in the US are getting tested more often than they did in the past and are living with HIV for a shorter period of time bef

Canada’s top doctors say Undetectable = Untransmittable

published: December, 04, 2017 Written by // Guest Authors - Revolving Door Categories // Social Media, Activism, As Prevention , Current Affairs, Treatment Guidelines -including when to start, Health, Research, Sexual Health, Revolving Door, Treatment, Guest Authors, Media

CATIE Executive Director Laurie Edmiston on the November 30 joint statement from Canada’s chief public health officer and the chief medical officers of health of all Canadian provinces and territories.

Canada’s top doctors say Undetectable = Untransmittable

It’s official! The Government of Canada supports U=U, the consensus statement that a person living with HIV does not transmit the virus sexually if they take treatment and maintain an undetectable viral load (“undetectable = untransmittable”). The news came on November 30 in a joint statement from Canada’s chief public health officer and the chief medical officers of health of all Canadian provinces and territories. “We have known for some time that ART [antiretroviral therapy] i

Creating a comprehensive cascade: CTAC issues call to action

published: December, 01, 2017 Written by // Guest Authors - Revolving Door Categories // Social Media, Activism, As Prevention , Current Affairs, Treatment Guidelines -including when to start, Research, Health, Treatment, Revolving Door, Living with HIV, Guest Authors, Media

To achieve and exceed the three 90-90-90-targets, two new targets are proposed

Creating a comprehensive cascade: CTAC issues call to action

As we approach World AIDS Day on December 1, CTAC is sending a strong message that “we’re not going away” by reaching out to select policymakers and their critics at all levels of government across Canada. We are providing them with an update on the issues of access to HIV and HCV treatment and care across Canada. CTAC was created by HIV positive leaders in 1996 to ensure access to treatment, care and support for people living with HIV/AIDS and people living with HIV/hepatitis C co-infe

It’s time to retire Canada’s AIDS epidemic

published: December, 01, 2017 Written by // Guest Authors - Revolving Door Categories // Social Media, As Prevention , CATIE, General Health, Treatment Guidelines -including when to start, Mental Health, Research, Health, CATIE - HIV and Hep C Info Resource, Revolving Door, Treatment, Guest Authors, Media, Opinion Pieces

For World AIDS Day 2017, PositiveLite.com is proud to present this guest editorial by CATIE Executive Director, Laurie Edmiston.

It’s time to retire Canada’s AIDS epidemic

Having turned 60 two months ago, I know there’s nothing quite like a milestone birthday to force you to get serious about your priorities and your future. The HIV response is facing our own wake-up call this December 1 as we mark the 30thWorld AIDS Day – a milestone I never imagined we would reach when I started working in HIV, 30 years ago. I have spent more than half of my life working in the HIV response, and while our goals have remained unchanged – reducing HIV infections and kee

Big win for U=U! Canada’s Chief Medical Officers of Health say “effectively no risk’ of HIV transmission via sex if viral load suppressed.

published: December, 01, 2017 Written by // Guest Authors - Revolving Door Categories // Social Media, As Prevention , Current Affairs, Treatment Guidelines -including when to start, General Health, Mental Health, Health, Research, Revolving Door, Treatment, Guest Authors, Media

PHAC World AIDS Day statement praises the Undetectable = Untransmittable (U=U) campaign and Indigenous Know Your Status program

Big win for U=U! Canada’s Chief Medical Officers of Health say “effectively no risk’ of HIV transmission via sex if viral load suppressed.

Statement on behalf of the Council of Chief Medical Officers of Health Statements From Public Health Agency of Canada November 30, 2017 Ottawa, ON Government of Canada Every year on December 1st, we come together to mark World AIDS Day and the start of Aboriginal AIDS Awareness Week.  There was a time not long ago when many lives were lost to AIDS in Canada. Thanks to advances in treatment, the situation today is vastly different. With timely interventions and supports, people living wit

Despite reassuring data, we can’t yet say U=U for breastfeeding

published: November, 27, 2017 Written by // Guest Authors - Revolving Door Categories // International AIDS Conference , Social Media, As Prevention , Current Affairs, Treatment Guidelines -including when to start, Research, International , Revolving Door, Treatment, Guest Authors, Media

Clinicians in high-income countries should take a harm reduction advice approach with HIV-positive mothers who breastfeed. From AIDSmap, Roger Pebody reports.

Despite reassuring data, we can’t yet say U=U for breastfeeding

While effective HIV treatment greatly reduces the risk of onward transmission during breastfeeding, it does not appear that the risk is zero, a leading paediatrician told the British HIV Association (BHIVA) conference in London last week. Although formula feeding is the safest option in high-income countries, some women will choose to breastfeed and healthcare professionals should support them to do so as safely as possible. Dr Hermione Lyall of St Mary's Hospital, London said that she and

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