A cure really? For many of us the idea of a cure for HIV/AIDS sounds so foreign –like it is only possible in a different galaxy or a different lifetime. For the past 14 years since 1996, the birth of HAART, HART or ART –however one chooses to call it, we have been sold the idea that HAART is as good as it gets. New drugs are often the reinvention of another drug, with
similar crappy side effects and a few novel drugs have made it to the market.
Millions of people are employed in the business of HIV/AIDS and billions are profited from sales of the HAART, both generic and brand name. PHAS in the western hemisphere have the option of claiming disability and live on limited income. However if live in a country with no social assistance, it means getting up every day and earning your bread; regardless of whether you are sick, low CD+, high viral load, TB, malaria, and may have no access to generic or brand name HAART. And we call HIV, a chronic manageable disease vs. a death sentence. What is morally and ethically wrong with this label?
In the midst of all this unresolved issues in 30 years of the AIDS epidemic, we have the highly glamorized AIDS 2010 Conference in Vienna for the western world. In between that we have the Asia Pacific AIDS Conference for the other half of the world. I was lucky enough of attend it last year in Bali on my way home to Malaysia. I have been to my fair share of AIDS International conferences, the horror for me –is the amount of money that is spent and what do we exactly accomplish not to mention the exorbitant registration fees. For the IAS, the AIDS International conference is a fund raiser of sorts.
Many of us have long forgotten the possibility that we might one day live without HIV in our bodies and in our life, what would that be like? What would it be, to never see another anti-HIV drug, what would it mean to have a sex anyway you wanted, what would it mean to eat anything without the worry of cholesterol or triglycerides? What would it be to live without fatigue, stigma, discrimination, or fear of disclosure? What would it mean to be able to travel to any country and not fear arrest or detention by immigration officers? What would it mean to live without the fear of having missed a darn pill, drug resistance, lipodystrophy, or bone loss due to HIV, or HIV associated neurocognitve disorder, and the hundreds of issues we negotiate daily in our lives? Yes HIV sucks –but we have coped and have resilience, and no we do not get a medal. But it does not mean we have stop dreaming the impossible- a Cure!
At least one group the AIDS Policy Project, http://www.aidspolicyproject.org/ in Philadelphia, has never stopped dreaming on the impossible. The group has just released a report, at http://www.aidspolicyproject.org/documents/The%20Cure%20Final.pdf "contending that a cure for AIDS may be closer to fruition than most people think, but lack of research dollars is holding it back."
"Who knows exactly what's going on with AIDS cure research?" ask Kate Krauss, Stephen LeBlanc and John James, the activists who wrote the report. They argue "that most people outside of the research community don't know how close we may be to a cure, nor how much funding is being spent toward a cure. This includes reporters, members of Congress and the public at large." And for the matter most researchers, HIV activist and treatment advocates in Canada have no clue what is happening in the area of research for a cure or HIV vaccines, preventative or therapeutic. And sadly, "millions of lives are at stake" and HIV infection is not decreasing but increasing worldwide.
The authors of this report define a cure as "either completely eradicating HIV from the body or teaching the immune system to control the virus." Then they give an example of one person who apparently has already been cured. The man, who received a bone marrow transplant due to aggressive leukemia, was given cells that are naturally resistant to HIV. More than two years later, he still has no detectable HIV in his body. Research building on this case is already underway, along with a number of other approaches."
The report alleges, "that funding for cure research at the National Institutes of Health (NIH) is about one fifth of what it should be or less than 3 percent of its AIDS budget on cure research," they note. The authors are calling on US Congress to increase the NIH budget by 20 percent.
Beyond funding, the activists are also calling on the AIDS research community to spur innovation, to be more open to scientists working in other areas and to openly declare—to other researchers and to patients—that their goal is a cure.
Throughout the report, the authors stress that a cure for HIV is not only possible, but even within reach if sufficient funding is available. And therein lies the problem. The dream can only manifest IF there is enough of political will-power, advocacy and activism from the HIV community of researchers, funding bodies, ASOs, policy analysts, PHAS and allies to push forward to maintain the funding and encourage collaboration between researchers.
I believe we can realize the dream and a cure is closer than we dare to dream.
Ref: http://www.poz.com/articles/hiv_cure_nih_761_18717.shtml